Mr. Subash Das (M.pharma)
- House no: b001
- Gr building
- Near divya msr gateway
- Gokula, mathikere
- Ms ramaiah road
- Bangalore-560054
- Phone +91-9900035899
- Email id – dassubash3@yahoo.co.in.
Research Area
Drug Delivery, Drug formulation, Drug designing, Molecular Biology
Research Description
- Expertise in development of Patent non-infringement or design around” formulations of solid oral dosage for US/EU market.
- Expertise in following technologies related to solid oral dosage forms: wet granulation, Roll compaction and fluid bed processing.
- Expertise in development of both immediate and modified release products.
- Expertise in development of various dosage forms of an antimicrobial agent used for urinary tract infection.
- Successfully developed and filled more than 15 generic products for US and EU market.
- Expertise in formulation development of NCE molecules from preclinical stage to clinical Phase I, Phase II stage. Successfully developed formulations for two NCE molecules for Phase I and Phase II clinical trials.
- Knowledge on bioavailability enhancement of NCE molecules. Developed formulation with 3 fold increase in bioavailability
- Development of nanosuspensions for NCE molecules by using high pressure homogenizer.
- Excellent knowledge on lyophilization cycle development for pharmaceuticals and biopharmaceuticals. Successfully developed lyophilization cycle for one biopharmaceutical long acting injectable formulation.
- Good knowledge on characterization techniques used for lyophilization process.
Selected Publication
- S. Das, B. Rambabu and J. G. Avari. Melt Spheronization Process for the Preparation of Sustained Release Pellets. 6th International Symposium on Advances in Technology and Business Potential of NDDS, Controlled Release Society Indian Chapter, Mumbai, 2005.
- B. Rambabu, S. Das, S.B. Jaiswal and J.G. Avari.Effect of Formulation and Process Variables on Release of Diltiazem Hydrochloride from the Wax Matrix Tablet. 6th International Symposium on Advances in Technology and Business Potential of NDDS, Controlled Release Society Indian Chapter, Mumbai, 2005
- Biswal S, Sahoo J, Murthy PN, Giradkar RP, Das S, Avari JG.Production variables affecting characteristics of pellets in melt pelletization with wax combination in a laboratory scale spheronizer, Acta Pharm. 2009 Jun;59(2):199-210. doi: 10.2478/v10007-009-0013-z.